发明名称 |
6-[(ЗАМЕЩЕННЫЙ)ФЕНИЛ]ТРИАЗОЛОПИРИМИДИНЫ В КАЧЕСТВЕ ПРОТИВОРАКОВЫХ ПРЕПАРАТОВ |
摘要 |
This invention relates to certain 6-[(substituted)phenyl]triazolopyrimidine compounds or pharmaceutically acceptable salts thereof, and compositions containing said compounds or pharmaceutically acceptable salts thereof, wherein said compounds are anti-cancer agents useful for the treatment of cancer in mammals. This invention further relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal and further provides a method for the treatment or prevention of cancerous tumors that express multiple drug resistance (MDR) or are resistant because of MDR, in a mammal in need thereof which method comprises administering to said mammal an effective amount of said compounds or pharmaceutically acceptable salts thereof. The present invention relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal in need thereof by promotion of microtubule polymerization which comprises administering to said mammal an effective amount of said compounds and pharmaceutically acceptable salts thereof. |
申请公布号 |
RU2006107579(A) |
申请公布日期 |
2007.10.27 |
申请号 |
RU20060107579 |
申请日期 |
2004.09.17 |
申请人 |
ВАЙЕТ ХОЛДИНГЗ КОРПОРЕЙШН (US) |
发明人 |
ЖАНГ Нан (US);АЙРАЛ-КАЛУСТЯН Семирамис (US);НГУЙЕН Тай Хайп (US);ВУ Янжонг (US);ТОНГ Вей (US) |
分类号 |
C07D487/04;A61P35/00;A61P35/04 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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