发明名称 |
Recombinant virus expressing foreign DNA encoding feline CD86 and uses thereof |
摘要 |
The present invention involves a recombinant virus which comprises at least one foreign nucleic acid inserted within a non-essential region of the viral genome of a virus, wherein each such foreign nucleic acid encodes a protein. The protein which is encoded is selected from the groups consisting of a feline CD28 protein or an immunogenic portion thereof, a feline cD80 protein or an immunogenic portion thereof, a feline CD86 protein or an immunogenic portion thereof, or a feline CTLA-4 protein or an immunogenic portion thereof. The protein is capable of being expressed when the recombinant virus is introduced into an appropiate host. The present invention also involves a recombinant virus further comprising a foreign nucleic acid encoding an immunogen derived from a pathogen. The present invention also comprises recombinant viruses which are capable of enhancing an immune response in a feline. The present invention also comprises recombinant viruses which are capable of suppressing an immune respons in a feline. |
申请公布号 |
US7279168(B2) |
申请公布日期 |
2007.10.09 |
申请号 |
US19990303040 |
申请日期 |
1999.04.30 |
申请人 |
SCHERING-PLOUGH ANIMAL HEALTH CORPORATION |
发明人 |
WINSLOW BARBARA J.;COCHRAN MARK D.;HASH STEPHEN;CHOI INSOO;COLLISSON ELLEN |
分类号 |
A61K39/00;A61K38/17;A61K39/02;A61K39/12;A61K39/205;A61K39/21;A61K39/39 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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