PROTEIN MARKERS FOR DIAGNOSING OF COLON RECTAL CANCER AND USE OF SAID MARKERS AS DRUG TARGETS FOR THE TREATMENT OF SAID CANCER TYPE
摘要
This invention relates to a method for diagnosing colorectal cancer (CRC) in a mammal, such as a human, the method comprising determining the presence, absence or level of expression of at least one marker protein in a biological sample from said mammal. It is demonstrated that the combination of metabolic labelling of colon biopsies from both normal and tumour tissues followed by 2 dimensional gel electrophoresis and mass spectrometry is a powerful tool in the identification of marker proteins involved in the development of CRC.
申请公布号
WO2007020522(A2)
申请公布日期
2007.02.22
申请号
WO2006IB02235
申请日期
2006.08.17
申请人
DRUGMODE APS;LARSEN, PETER, MOSE;FEY, STEPHEN, JOHN