| 发明名称 |
Inhibitors of signal transduction and activator of transcription 3 |
| 摘要 |
Stat3 inhibitor compounds are disclosed, wherein the compounds are structural analogs of Ac-pTyr-Leu-Pro-Gln-Thr-NH<SUB>2 </SUB>and bind to the SH2 domain of Stat3 under physiological conditions to inhibit a cellular signaling activity of Stat3.
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| 申请公布号 |
US2007010428(A1) |
申请公布日期 |
2007.01.11 |
| 申请号 |
US20050219530 |
申请日期 |
2005.09.02 |
| 申请人 |
MCMURRAY JOHN S;REN ZHIYONG;COLEMAN DAVID R IV;MANDAL PIJUS K;CHEN XIAOMIN;LIAO WARREN |
发明人 |
MCMURRAY JOHN S.;REN ZHIYONG;COLEMAN DAVID R.IV;MANDAL PIJUS K.;CHEN XIAOMIN;LIAO WARREN |
| 分类号 |
A61K38/08;A61K38/05;A61K38/06 |
主分类号 |
A61K38/08 |
| 代理机构 |
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