发明名称 |
Method of reducing staining of stannous in dentifrice compositions |
摘要 |
Disclosed are methods for reducing the staining of dentifrice composition containing stannous comprising administering to a subject the dentifrice composition. The dentifrice composition is a dual phase dentifrice and is contained in physically separated compartments of a dentifrice dispenser. The first dentifrice composition comprises an effective amount of one or more linear polyphosphates having an average chain length of about 4 or more and has a total water content of up to about 20%. The second dentifrice composition comprises an effective amount of stannous ions. The molar ratio of polyphosphate anion to stannous ion is from about 0.2:1 to about 5:1 and the efficacy of the stannous ion in the dentifrice is not reduced by the polyphosphate. The dentifrice composition may alternatively be a single phase dentifrice. The single phase dentifrice will comprise an effective amount of one or more linear polyphosphates having an average chain length of about 4 or more and an effective amount of a stannous ion. The single phase dentifrice has a total water content of up to about 20%, the stannous ion is not delivered from stannous fluoride, a molar ratio of polyphosphate anion to stannous ion is from about 0.2:1 to about 5:1, and the efficacy of the stannous ion in the dentifrice is not reduced by the polyphosphate.
|
申请公布号 |
US7063833(B2) |
申请公布日期 |
2006.06.20 |
申请号 |
US20030694130 |
申请日期 |
2003.10.27 |
申请人 |
THE PROCTER & GAMBLE COMPANY |
发明人 |
GLANDORF WILLIAM MICHAEL;BACCA LORI ANN |
分类号 |
A61K8/46;A61K8/21;A61K8/24;A61Q11/00 |
主分类号 |
A61K8/46 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|