| 发明名称 |
METHODS OF REGULATING DIFFERENTIATION AND TREATING OF MULTIPLE MYELOMA |
| 摘要 |
The present invention provides methods of regulating cellular differentiation, including differentiation of stem cells and trans-differentiation of monocytes/macrophages using agonists or antagonists of pleiotrophin or a pleiotrophin receptor, as well as related methods of treating cancers associated with pleiotrophin-regulated differentiation and angiogenesis, including, e.g., multiple myeloma. |
| 申请公布号 |
WO2006020684(A2) |
申请公布日期 |
2006.02.23 |
| 申请号 |
WO2005US28362 |
申请日期 |
2005.08.10 |
| 申请人 |
EARCH INSTITUTE FOR MULTIPLE MYELOMA AND BONE CANCER RES;BERENSON, JAMES;HAIMING, CHEN;GORDON, MELINDA, S. |
发明人 |
BERENSON, JAMES;HAIMING, CHEN;GORDON, MELINDA, S. |
| 分类号 |
A61K31/00;A61K35/76;A61K38/18;A61P35/02;C12N5/071;C12N5/0786;C12N15/113;G01N33/574 |
主分类号 |
A61K31/00 |
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