发明名称 |
ILLUDIN ANALOGS AS ANTI-TUMOR AGENTS |
摘要 |
A method of inhibiting tumor cell growth in a subject is provided comprising contacting the tumor with a therapeutic amount of an illudin S or illudin M analog having structure (I) or (II), wherein the analog is capable of inhibiting tumor cell growth without excessive toxicity to the subject and wherein R1 is an alkyl or hydrogen; R2 is an alkyl; and R3 is an alcohol or ester.
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申请公布号 |
CA2067365(C) |
申请公布日期 |
2006.01.31 |
申请号 |
CA19902067365 |
申请日期 |
1990.10.02 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
KELNER, MICHAEL J.;MCMORRIS, TREVOR C.;TAETLE, RAYMOND |
分类号 |
C07C49/587;A61K31/12;A61K31/215;A61K31/22;A61K31/27;A61K47/48;A61P35/00;C07C45/45;C07C45/46;C07C45/65;C07C45/67;C07C49/665;C07C49/67;C07C49/683;C07C49/727;C07C49/737;C07C49/747;C07C49/753;C07C49/755;C07C69/007;C07C69/757;C07C271/12 |
主分类号 |
C07C49/587 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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