发明名称 Hydroxy cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists
摘要 The present invention provides substituted 10,11-Dihydro-5H-benzo[e]-pyrrolo[1,2-a][1,4]diazepine and 9,10-Dihydro-4H-3a,5,9-triaza-benzo[f]azulene compounds as well as methods and pharmaceutical compositions utilizing these compounds for the treatment and/or prevention and/or suppression of disorders which may be remedied or alleviated by oxytocin antagonist activity, including prevention and/or suppression of preterm labor, suppression labor at term prior to caesarean deliver, and for the treatment of dysmenorrhea. These compounds are also useful in enhancing fertility rates, enhancing survival rates and synchronizing estrus in farm animals.
申请公布号 US6977254(B2) 申请公布日期 2005.12.20
申请号 US20020119973 申请日期 2002.04.10
申请人 WYETH 发明人 FAILLI AMEDEO ARTURO;SANDERS WILLIAM JENNINGS;TRYBULSKI EUGENE JOHN
分类号 A61K31/5517;A61P5/12;A61P15/06;A61P43/00;C07D487/04;(IPC1-7):C07D487/04;C07D487/14;A61K31/551 主分类号 A61K31/5517
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