发明名称 Deleted sequences in M. bovis BCG/M bovis or M. tuberculosis, method for detecting mycobacteria using these sequences and vaccines
摘要 The subject of the present invention is the identification of nucleotide and peptide sequences which make it possible in particular to distinguish, in diagnostic terms, an immunization resulting from a BCG vaccination from an M. tuberculosis infection. The sequences in question are specific either to M. bovis BCG/M. bovis, or to M. tuberculosis. The subject of the present invention is also a method for detecting the sequences in question, a method for detecting antibodies generated by the products of expression of these sequences and the kits for carrying out these methods. Finally, the subject of the present invention is novel vaccines.
申请公布号 US2005250120(A1) 申请公布日期 2005.11.10
申请号 US20040980194 申请日期 2004.11.04
申请人 INSTITUT PASTEUR 发明人 COLE STEWART;GORDON STEPHEN;ROLAND BUCHRIESER-BROSCH;BILLAULT ALAIN;GARNIER THIERRY
分类号 A61P37/00;C07K14/35;C12N15/31;C12Q1/68;(IPC1-7):C12Q1/68;C07H21/04 主分类号 A61P37/00
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