发明名称 Ortho-substituted benzoic acid derivatives for thetreatment of insulin resistance.
摘要 The present invention provides a compound of formula (I), wherein n is 0, 1 or 2; R<1> represents halo, a C1-4alkyl group which is optionally substituted by one or more fluoro, a C1-4alkoxy group which is optionally substituted by one or more fluoro and wherein when n is 2 the substituents R<1> may be the same or different; R<2> represents an unbranched C2-7alkyl group; R<3> represents H or OCH3; and W represents O or S and pharmaceutically acceptable salts and prodrugs thereof, to processes for preparing such compounds, to their utility in treating clinical conditions associated with insulin resistance, to methods for their therapeutic use and to pharmaceutical compositions containing them.
申请公布号 ZA200409693(B) 申请公布日期 2005.10.11
申请号 ZA20040009693 申请日期 2004.11.30
申请人 ASTRAZENECA AB. 发明人 LANNA LI
分类号 A61P3/04;A61K;A61K31/19;A61K31/192;A61P;A61P3/06;A61P3/10;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P13/12;A61P25/00;A61P25/16;A61P25/28;A61P29/00;A61P35/00;A61P43/00;C07C;C07C235/20;C07C323/20;C07C323/62 主分类号 A61P3/04
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