| 摘要 |
FIELD: pharmaceutical industry, medicine. ^ SUBSTANCE: invention relates to peroral immediate-released drug in solid form, containing low molecular thrombin inhibitor based on peptide with pH-depending solubility. Claimed drug has size particle less than 300 mum and contains combination of microcrystal cellulose and sodium glycolate starch in amount of more than 35 mass % (calculates as preparation mass). ^ EFFECT: drug with reduced dependence of thrombin inhibitor dissolution from pH and increased releasing rate from tablet. ^ 17 cl, 3 ex, 3 dwg |
