| 摘要 |
PROBLEM TO BE SOLVED: To obtain a compound having CXCR3 antagonism. SOLUTION: The compound is represented by general formula (I), its salt, its solvate or its prodrug. Since the compound represented by general formula (I) has CXCR3 antagonism, the compound is useful for preventing/treating inflammations and allergic diseases [e.g. systemic inflammatory response syndrome (SIRS), anaphylaxis, anaphylaxis-like reaction, allergic angiitis, hepatitis, nephritis, nephropathy, pancreatitis, rhinitis, arthritis, inflammatory eye disease, inflammatory intestinal disease, cerebral and cardiovascular disease, respiratory disease, dermatosis, autoimmune disease, having, etc.], metabolic and endocrine disease [e.g. diabetes, etc.], cancer disease [e.g. malignant neoplasma, etc.], infectious disease and disease following infection [e.g. viral disease, AIDS, dementia, etc.], etc. COPYRIGHT: (C)2005,JPO&NCIPI
|
