| 发明名称 |
Arylsulfonamide derivatives for use as ccr3 antagonists in the treatment of inflammatory and immunological disorders |
| 摘要 |
The present invention relates to a sulfonamide derivative which is useful as an active ingredient of pharmaceutical preparations. The sulfonamide derivatives of the present invention have CCR3 (CC type chemokine receptor) antagonistic activity, and can be used for the prophylaxis and treatment of diseases associated with CCR3 activity, in particular for the treatment of asthma, atopic dermatitis, allergic rhinitis and other inflammatory/immunological disorders.
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| 申请公布号 |
US2005070582(A1) |
申请公布日期 |
2005.03.31 |
| 申请号 |
US20040489029 |
申请日期 |
2004.10.21 |
| 申请人 |
BAYER HEALTHCARE AG |
发明人 |
LI YINGFU;WATANABE AKIHIKO;LOWINGER TIMOTHY B.;BACON KEVIN;KAWAMURA NORIHIRO;SHINTANI TAKUYA;KIKUCHI TETSUO;MORIWAKI TOSHIYA;URBAHNS KLAUS;FUKUSHIMA KEIKO;NUNAMI NORIKO;YOSHINO TAKASHI;MURATA TOSHIKI;YAMAUCHI MEGUMI;YOSHINO HIROKO |
| 分类号 |
A61K31/18;A61K31/40;A61K31/4025;A61K31/4035;A61K31/437;A61K31/4375;A61K31/4406;A61K31/445;A61K31/4453;A61K31/4465;A61K31/4523;A61K31/454;A61K31/495;A61K31/496;A61K31/4985;A61K31/5375;A61K31/551;A61P5/16;A61P9/10;A61P11/02;A61P11/06;A61P25/28;A61P27/16;A61P29/00;A61P31/18;A61P35/00;A61P37/00;A61P37/02;A61P37/08;A61P43/00;C07C311/29;C07C323/67;C07D207/14;C07D207/48;C07D209/08;C07D209/44;C07D211/14;C07D211/26;C07D211/28;C07D211/58;C07D211/96;C07D213/65;C07D213/70;C07D213/71;C07D213/75;C07D213/76;C07D213/80;C07D241/04;C07D241/06;C07D243/08;C07D257/04;C07D295/088;C07D295/12;C07D295/13;C07D295/194;C07D295/22;C07D295/26;C07D307/14;C07D333/38;C07D333/40;C07D471/04;C07D487/04;C07D487/08;(IPC1-7):A61K31/44;C07D213/62 |
主分类号 |
A61K31/18 |
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