发明名称 |
PROMOTOR AUS ASHBYA GOSSYPII |
摘要 |
<p>Enzymes involved in purine biosynthesis in Ashbya gossypii are new. hosphoribosylpyrophosphate synthetases (KPR1 and 2) comprising 318 or 320 amino acid residues, glutamine-phosphororibosylpyrophosphate amidotransferase (ADE4) comprising 510 amino acid residues, IMP-dehydrogenase (GUA1) comprising 151 or 371 amino acid residues, and a GMP-synthetase (GUA2) comprising 525 amino acid residues or polypeptides with substitution, insertion or deletion of 10-20 % of the amino acid sequence, and the activity of the relative enzyme are new (all sequences fully defined in the specification). Independent claims are also included for: (1) nucleic acid sequences encoding the above enzymes; and (2) the production riboflavin comprising cultivation of a microorganism genetically modified with at least one gene for purine biosynthesis.</p> |
申请公布号 |
DE59812281(D1) |
申请公布日期 |
2004.12.23 |
申请号 |
DE1998512281 |
申请日期 |
1998.12.23 |
申请人 |
BASF AG |
发明人 |
REVUELTA DOVAL, JOSE LUIS;SANTOS GARCIA, MARIA ANGELES;POMPEJUS, MARKUS;SEULBERGER, HARALD |
分类号 |
C12N15/09;C07K14/39;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/00;C12N9/02;C12N9/04;C12N9/10;C12N9/12;C12N15/00;C12N15/52;C12N15/53;C12N15/80;C12P19/28;C12P25/00;C12R1/645 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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