METHOD OF SYNTHESIS AND TESTING OF COMBINATORIAL LIBRARIES USING MICROCAPSULES
摘要
The invention describes a method for the synthesis of compounds comprising the steps of: (a) compartmentalising two or more sets of primary compounds into microcapsules; such that a proportion of the microcapsules contains two or more compounds; and (b) forming secondary compounds in the microcapsules by chemical reactions between primary compounds from different sets. The invention further allows for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, and which is co-compartmentalised into the microcapsules.
申请公布号
WO2004087308(A1)
申请公布日期
2004.10.14
申请号
WO2004GB01352
申请日期
2004.03.31
申请人
MEDICAL RESEARCH COUNCIL;GRIFFITHS, ANDREW, DAVID;ABELL, CHRIS;HOLLFELDER, FLORIAN;MASTROBATTISTA, ENRICO