SOLID DOSAGE FORM COMPRISING KETOPROFEN

摘要

An edible solid composition comprises: (a) about 25 to about 40 weight percent of at least one non-aqueous carrier material which has a melting temperature less than about 45 degrees C; and (b) about 15 to about 60 weight percent of at least one thermoplastic material which has a melting temperature greater than about 50 degrees C. The composition may optionally additionally contain up to about 40 weight percent of at least one compatibility material for retaining the non-aqueous carrier material in the edible solid composition. The compatibility material is selected from the group consisting of emulsifiers, acrylic polymers, waxes and combinations thereof. The edible solid composition may be used as a core or shell in a dosage form, or as a dosage form per se which contains or is prepared from such an edible solid composition.