| 发明名称 |
NEUROPEPTIDE RECEPTOR AND USES THEREOF |
| 摘要 |
This invention relates to the identification of an orphan G-protein coupled receptor MRGX2 (and variants thereof) as a receptor of neuropeptides such as but not limited to cortistatin, somatostatin, Bam 13-22, alpha -MSH, neuropeptide FF, dynorphin A and substance P, and the use of such neuropeptides (and structurally related molecules) as modulators for MRGX2. It also relates to screening methods to identify agonists and antagonists for this neuropeptide receptor. |
| 申请公布号 |
WO03073107(A3) |
申请公布日期 |
2004.03.04 |
| 申请号 |
WO2003IB00601 |
申请日期 |
2003.02.17 |
| 申请人 |
PFIZER LIMITED;FIDOCK, MARK, DAVID;ROBAS, NICOLA, MELANIE;PFIZER INC. |
发明人 |
FIDOCK, MARK, DAVID;ROBAS, NICOLA, MELANIE |
| 分类号 |
A61K38/00;A61K38/17;A61K45/00;A61P1/00;A61P3/04;A61P3/10;A61P9/00;A61P13/02;A61P13/10;A61P15/00;A61P25/04;A61P25/20;A61P25/24;A61P25/28;A61P29/00;A61P29/02;A61P35/00;C07K14/705;C12N15/09;C12P21/02;C12Q1/02;G01N33/15;G01N33/50;G01N33/74 |
主分类号 |
A61K38/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
