1-CARBOXYMETHYL ANALOGUES OF GLUCOSYL LIPID A

摘要

Compounds represented by the general formula (I), or pharmacologically acceptable salts or ester thereof; and pharmaceutical compositions containing the same as the active ingredient: (I) wherein R<1> is hydrogen, C1-20 alkyl, C2-20 alkenyl, C2-20 alkynyl, or the like; R<2> and R<4> are each independently, hydrogen, C1-20 alkyl, C2-20 alkenyl, C2-20 alkynyl, C1-20 alkanoyl, C3-20 alkenoyl, C3-20 alkynoyl, or the like; R<3> is C1-20 alkanoyl, C3-20 alkenoyl, C3-20 alkynoyl, or the like; and R<5> is hydrogen, halogeno, hydroxyl, C1-6 alkoxy, C2-6 alkenyloxy, C2-6 alkynyloxy, or the like.