发明名称 |
SOLUBILIZED TOPOISOMERASE POISON AGENTS |
摘要 |
The invention provides compounds of formula (I): wherein A, B, W, Y, Z, and R<sb>1</sb> have any of the meanings defined in the specification and their pharmaceutically acceptable salts. The invention also provides pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I, and therapeutic methods for treating cancer using compounds of formula I. |
申请公布号 |
WO03051289(A2) |
申请公布日期 |
2003.06.26 |
申请号 |
WO2002US36475 |
申请日期 |
2002.11.14 |
申请人 |
RUTGERS, THE STATE UNIVERSITY;LAVOIE, EDMOND, J.;RUCHELMAN, ALEXANDER, L. |
发明人 |
LAVOIE, EDMOND, J.;RUCHELMAN, ALEXANDER, L. |
分类号 |
A61K31/4745;A61K31/5025;A61K31/503;A61P17/06;A61P31/04;A61P31/10;A61P31/12;A61P33/02;A61P35/00;A61P43/00;C07D491/14;C07D491/147 |
主分类号 |
A61K31/4745 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|