| 摘要 |
<p>Compounds represented by the following general formula (I) or salts thereof: (I) wherein R1 represents hydrogen, halogeno, hydroxy, nitro, optionally halogenated alkyl, optionally substituted alkoxy, acyl or optionally substituted amino; R2 represents pyridyl, furyl, thienyl, pyrolyl, quinolyl, pirazinyl, pyrimidinyl, pyridazinyl, indolyl, tetrahydroquinolyl or thiazolyl, each optionally substituted; and n is 1 or 2; and preventives/remedies, which contain the compounds of the general formula (I) and have a high safety and favorable effects of inhibiting cell death and binding to MIF, for heart diseases, neurodegenerative diseases, brain vascular diseases, central nerve infections, traumatic diseases, demyelinating diseases, bone/joint diseases, kidney diseases, liver diseases, myelodysplastic syndrome, AIDS, cancer, etc.</p> |
