发明名称 |
PROTEIN-POLYCATION CONJUGATES |
摘要 |
New protein-polycation conjugates which are capable of forming soluble complexes with nucleic acids contain as their protein component an antibody directed against a cell surface protein, with the ability to bind to the cell surface protein so that the complexes formed are absorbed into cells which express the cell surface protein and are expressed therein. Complexes for use in pharmaceutical preparations contain a therapeutically or gene therapeutically active nucleic acid.
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申请公布号 |
US2003027773(A1) |
申请公布日期 |
2003.02.06 |
申请号 |
US19930098268 |
申请日期 |
1993.08.05 |
申请人 |
BIRNSTIEL MAX L.;COTTEN MATTHEW;WAGNER ERNST |
发明人 |
BIRNSTIEL MAX L.;COTTEN MATTHEW;WAGNER ERNST |
分类号 |
A61K31/70;A61K39/395;A61K47/48;A61K48/00;C12N1/15;C12N15/87;(IPC1-7):A61K48/00;C07K16/40;C07H21/04 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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