发明名称 N-(3-AMINO-2-HYDROXY-PROPYL) SUBSTITUTED ALKYLAMIDE COMPOUNDS
摘要 Disclosed are compounds of the formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the betasecretase enzyme that are useful in the treatment of Alzeheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
申请公布号 WO03006423(A1) 申请公布日期 2003.01.23
申请号 WO2002US22255 申请日期 2002.07.11
申请人 ELAN PHARMACEUTICALS, INC.;PHARMACIA & UPJOHN COMPANY;GAILUNAS, ANDREA;HOM, ROY;JOHN, VARGHESE;MAILLARD, MICHEL;CHRUSCIEL, ROBERT, ALAN;FISHER, JED;JACOBS, JON;FRESKOS, JOHN, N.;BROWN, DAVID, L.;FOBIAN, YVETTE, M. 发明人 GAILUNAS, ANDREA;HOM, ROY;JOHN, VARGHESE;MAILLARD, MICHEL;CHRUSCIEL, ROBERT, ALAN;FISHER, JED;JACOBS, JON;FRESKOS, JOHN, N.;BROWN, DAVID, L.;FOBIAN, YVETTE, M.
分类号 A61K31/164;A61K31/165;A61K31/275;A61K31/343;A61K31/352;A61K31/357;A61K31/36;A61K31/381;A61K31/401;A61K31/4015;A61K31/4035;A61K31/404;A61K31/41;A61K31/4155;A61K31/4178;A61K31/4184;A61K31/4196;A61K31/423;A61K31/4245;A61K31/426;A61K31/428;A61K31/4402;A61K31/4409;A61K31/4412;A61K31/4439;A61K31/45;A61K31/495;A61K31/50;A61K31/505;A61K31/52;A61K31/536;A61P25/00;A61P25/28;A61P43/00;C07C233/22;C07C233/35;C07C233/40;C07C235/20;C07C235/34;C07C235/78;C07C271/16;C07C271/22;C07C311/06;C07C323/62;C07D207/16;C07D207/26;C07D207/27;C07D207/32;C07D207/327;C07D207/333;C07D207/337;C07D209/08;C07D209/12;C07D209/18;C07D209/30;C07D209/46;C07D209/48;C07D211/22;C07D211/76;C07D213/38;C07D213/56;C07D213/64;C07D213/69;C07D213/74;C07D213/89;C07D231/12;C07D233/54;C07D233/60;C07D233/64;C07D235/08;C07D235/16;C07D235/26;C07D237/14;C07D239/20;C07D239/54;C07D241/08;C07D241/12;C07D249/04;C07D249/08;C07D249/12;C07D249/18;C07D257/04;C07D261/10;C07D263/56;C07D263/57;C07D263/58;C07D265/14;C07D265/18;C07D271/06;C07D275/04;C07D275/06;C07D277/20;C07D277/34;C07D277/36;C07D277/44;C07D277/46;C07D277/64;C07D277/70;C07D295/08;C07D295/088;C07D295/14;C07D295/155;C07D307/14;C07D307/52;C07D307/54;C07D307/79;C07D307/80;C07D307/81;C07D307/91;C07D311/58;C07D311/74;C07D317/28;C07D317/60;C07D319/18;C07D321/02;C07D321/10;C07D333/22;C07D333/24;C07D333/54;C07D401/04;C07D403/04;C07D405/04;C07D409/04;C07D413/04;C07D417/04;C07D473/02;C07D473/08;C07D487/04;(IPC1-7):C07C233/35 主分类号 A61K31/164
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