发明名称 USE OF COMPOUNDS AS FUNCTIONAL ANTAGONISTS TO THE CENTRAL CANNABINOID RECEPTORS
摘要 The invention refers to the use of saturated fatty acid acylamide derivatives as functional antagonists to the central cannabinoid receptors. These molecules, per se devoid of the psychotropic effects of classic cannabinoids, aminoalkylindoles, endocannabinoids known today, have the ability to behave as functional antagonists of the central cannabinoid receptors, when administered by different routes. For their pharmacological activity they are therefore suitable as drugs in pathological states or disorder which can be controlled through a reduction in the functionality of said receptors or through a reduction of the effect of the same endocannabinoids also caused by a reduced availability or affinity of the receptors.
申请公布号 WO03006007(A1) 申请公布日期 2003.01.23
申请号 WO2002EP07722 申请日期 2002.07.11
申请人 RESEARCH & INNOVATION SOC.COOP. A R.L.;LEON, ALBERTA;DALLE CARBONARE, MAURIZIO 发明人 LEON, ALBERTA;DALLE CARBONARE, MAURIZIO
分类号 A61K31/195;A61P1/00;A61P1/16;A61P25/00;A61P25/30;A61P37/00;(IPC1-7):A61K31/195 主分类号 A61K31/195
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