ANTI_HUMAN OVARIAN CANCER -ANTI_CD3 BISPECIFIC ANTIBODY

摘要

The invention provides an anti-ovarian cancer bispecific antibody, said antibody includes two polypeptide domains connected by a polypeptide linker, one is anti- ovarian cancer antibody, or its Fab fragment, single complementarity determining region(CDR) antibody or single chain Fv (scFv), the other is anti-CD3 antibody, or its Fab fragment, single CDR antibody, or scFv. The invention also provides DNA sequences encoding said antibody, an expression vector containing said DNA sequence, and an host cell containing said expression vector.