| 摘要 |
PROBLEM TO BE SOLVED: To obtain a compound capable of controlling production of inflammatory cytokine. SOLUTION: This compound is represented by general formula (I) A is furan, thiophene, pyrazole, imidazole, isoxazole, isothiazole or the like; R<1> is a substitutable aryl or a substitutable heteroaryl; R<2> is a substitutable heteroaryl; and R<3> is a bicyclic amino group with the proviso that atoms on the pyrrole ring to which R<1> and R<3> are bonded are adjacent to an atom on the pyrrole ring to which R<2> is bonded, respectively) or its pharmacologically acceptable salt, ester or other derivative.
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