| 主权项 |
1. A compound of formula (I)or a pharmaceutically acceptable salt or an ester prodrug thereof, wherein:
T is a double bond; R1 is selected from the group consisting of: COOR7, CONR7R8, COSR7, COR7, SO3H, SO2NR7R8, SO2R7, SONR7R8, and SOR7; R2, R3, and R4 are each independently selected from the group consisting of: H, optionally substituted C1-C12 alkyl, and optionally substituted C2-C12 alkenyl; R5 and R6 are each independently selected from the group consisting of: H, OH, optionally substituted C1-C12 alkyl, ═O, (CH2)mOC(O)R9, C1-C12 oxyalkyl, C1-C12 alkyloxy, C2-C12 oxyalkenyl, and C2-C12 alkenyloxy, provided at least one of R5 and R6 is (CH2)mOC(O)R9; R7 and R8 are each independently selected from the group consisting of: H, optionally substituted C1-C12 alkyl, optionally substituted C2-C12 alkenyl, optionally substituted C2-C12 alkynyl, optionally substituted C1-C10 heteroalkyl, optionally substituted C3-C12 cycloalkyl, optionally substituted C3-C12 cycloalkenyl, optionally substituted C1-C12 heterocycloalkyl, optionally substituted C1-C12 heterocycloalkenyl, optionally substituted C6-C18 aryl, and optionally substituted C1-C18 heteroaryl; R9 is phenyl; Ar is an optionally substituted aryl group; and m and n are integers each of which is selected from the group consisting of 0, 1, 2, 3, and 4. |
