| 发明名称 |
HIGH AFFINITY SOLUBLE INTERLEUKIN-18 RECEPTOR |
| 摘要 |
A soluble, heterodimeric interleukin 18 (IL-18) receptor molecule is described which comprises two subunits, one of which comprises an extracelluar domain, or a fragment thereof, of IL-18R, and the other of which comprises an extracelluar domain, or a fragment thereof, of AcPL. Preferably, the soluble, heterodimeric receptor binds to IL-18 with higher affinity than does either IL-18R or AcPL alone. |
| 申请公布号 |
WO0208272(A2) |
申请公布日期 |
2002.01.31 |
| 申请号 |
WO2001US22863 |
申请日期 |
2001.07.20 |
| 申请人 |
SCHERING AKTIENGESELLSCHAFT;LEUNG, STEWART;PEREZ, H., DANIEL;MIYAMOTO, NEIL |
发明人 |
LEUNG, STEWART;PEREZ, H., DANIEL;MIYAMOTO, NEIL |
| 分类号 |
G01N33/53;A61K38/00;A61P19/02;A61P21/00;A61P25/28;A61P29/00;A61P37/00;A61P43/00;C07K14/715;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/12;C12P21/02;G01N33/566 |
主分类号 |
G01N33/53 |
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