LIPID-BASED DRUG DELIVERY SYSTEMS CONTAINING PHOSPHOLIPASE A2 DEGRADABLE LIPID DERIVATIVES FOR MEDICAL USE AGAINST PARASITIC INFECTIONS

摘要

The present invention is directed to a lipid-based delivery system for administration of an active drug substance selected from lysolipid derivatives which are particularly useful in the treatment or detection of parasitic infections, especially parasitic infections which cause an elevated PLA2 level in the infected mammal. Preferred parasitic infections are infections wherein the life cycle of the parasite involves the liver and/or spleen of the infected organism.