发明名称 |
HYDRAZIDE DERIVATIVES |
摘要 |
Novel hydrazide derivatives represented by the following general formula (I). Because of having an excellent activity of inhibiting apo B-associated lipoprotein secretion, these hydrazide derivatives are useful as drugs for hyperlipemia, preferably cholesterol- or triglyceride-lowering agents wherein the ring A is an optionally substituted benzene or pyridine ring; Z1 represents lower alkylene; R1 to R3 may be the same or different and each represents H, hydrocarbyl, a heterocycle, etc.; R4 to R6 may be the same or different and each represents H, halogeno, hydrocarbyl, etc.; and R7 to R9 may be the same or different and each represents H, hydrocarbyl, etc.
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申请公布号 |
WO0174817(A1) |
申请公布日期 |
2001.10.11 |
申请号 |
WO2001JP02674 |
申请日期 |
2001.03.29 |
申请人 |
YAMANOUCHI PHARMACEUTICAL CO., LTD.;SUGA, AKIRA;MIURA, MASANORI;IMANISHI, NAOKI;KUBOTA, HIDEKI;MORITANI, HIROSHI |
发明人 |
SUGA, AKIRA;MIURA, MASANORI;IMANISHI, NAOKI;KUBOTA, HIDEKI;MORITANI, HIROSHI |
分类号 |
A61K31/519;C07D487/04;(IPC1-7):C07D487/04;C07D471/14;A61P3/06 |
主分类号 |
A61K31/519 |
代理机构 |
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