| 发明名称 |
SYNTHESIS OF EPOTHILONES, INTERMEDIATES THERETO AND ANALOGUES THEREOF |
| 摘要 |
The present invention provides convergent processes for preparing epothilone s, desoxyepothilones, and analogues thereof. The present invention further provides novel compositions and methods for the treatment of cancer and additionally provides methods for the treatment of cancer which has develope d a multi-drug phenotype.
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| 申请公布号 |
CA2401800(A1) |
申请公布日期 |
2001.09.07 |
| 申请号 |
CA20012401800 |
申请日期 |
2001.03.01 |
| 申请人 |
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH;THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK |
发明人 |
STACHEL, SHAWN;CHOU, TING-CHAO;CHAPPELL, MARK;LEE, CHUL BOM;DANISHEFSKY, SAMUEL J.;WU, ZHICAL |
| 分类号 |
C07D277/24;A61K31/337;A61K31/427;A61K31/475;A61K31/704;A61K47/48;A61P35/00;A61P35/02;A61P41/00;A61P43/00;C07B61/00;C07C45/64;C07C49/24;C07C68/00;C07C69/96;C07C327/28;C07D417/06;C07D417/14;C07D491/044;C07D493/04;C07F7/18;(IPC1-7):C07D225/02;C07D315/00 |
主分类号 |
C07D277/24 |
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