发明名称 |
CHIMERIC PEPTIDES AS IMMUNOGENS, ANTIBODIES THERETO, AND METHODS FOR IMMUNIZATION USING CHIMERIC PEPTIDES OR ANTIBODIES |
摘要 |
The invention provides a chimeric peptide or mixture of chimeric peptides that can be formulated as an immunizing composition and used in a method for immunization of a mammal against an internal peptide cleavage product derived from a precursor or mature protein, for which the peptide cleavage product and the precursor or mature protein are self molecules. The chimeric peptide or peptides have an end-specific B cell epitope from a naturally-occurring internal peptide cleavage product of a precursor or mature protein, as a free N- or C- terminus, fused with or without spacer residues to a T helper cell epitope derived from a living source different from that of the internal peptide cleavage product.
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申请公布号 |
WO0142306(A2) |
申请公布日期 |
2001.06.14 |
申请号 |
WO2000US33203 |
申请日期 |
2000.12.08 |
申请人 |
MINDSET BIOPHARMACEUTICALS (USA), INC.;CHAIN, BENJAMIN |
发明人 |
CHAIN, BENJAMIN |
分类号 |
C12P21/08;A61K38/00;A61K39/00;A61K39/39;A61K39/395;A61P25/28;C07K14/47;C07K16/18;C07K19/00;C12N15/62;(IPC1-7):C07K14/705 |
主分类号 |
C12P21/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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