ANTI-INFLAMMATORY INDOLE DERIVATIVES

摘要

Compounds of formula (I) or a pharmaceutically acceptable salt, in vivo hydrolysable ester, or amide thereof, where X is CH2 or SO2; R<1> is an optionally substituted aryl or heteroaryl ring; R<4> is a group OR<15> or S(O)qR<15>, where q is 0, 1 or 2 and R<15> is a substituted hydrogen-containing alkyl group; and R<2>, R<3>, R<5>, R<6> and R<7> are specified organic groups. These compounds are useful in therapy, in particular of inflammatory disease, and methods of producing them as well as pharmaceutical compositions containing them are also described and claimed.