PROCESS FOR PREPARING 1,5-DIARYL-3-SUBSTITUTED PYRAZOLES
摘要
A process for making a compound of formula (I) wherein the substituents are as described in the specification comprising reacting a ketone of formula (II) with succinic anhydride and an alkoxide base to form a compound of formula (III) which is reacted with a compound of formula (IV) to form a compound of formula (V) and reacting with an alcohol to form the corresponding ester of formula (VI) and reacting the ester with <i>N</i>-methylhydroxylamine.
申请公布号
WO0109102(A2)
申请公布日期
2001.02.08
申请号
WO2000US20917
申请日期
2000.08.01
申请人
ORTHO-MCNEIL PHARMACEUTICAL, INC.
发明人
ABDEL-MAGID, AHMED, F.;HARRIS, BRUCE, D.;MARYANOFF, CYNTHIA, A.