发明名称 PROCESS FOR PREPARING 1,5-DIARYL-3-SUBSTITUTED PYRAZOLES
摘要 A process for making a compound of formula (I) wherein the substituents are as described in the specification comprising reacting a ketone of formula (II) with succinic anhydride and an alkoxide base to form a compound of formula (III) which is reacted with a compound of formula (IV) to form a compound of formula (V) and reacting with an alcohol to form the corresponding ester of formula (VI) and reacting the ester with <i>N</i>-methylhydroxylamine.
申请公布号 WO0109102(A2) 申请公布日期 2001.02.08
申请号 WO2000US20917 申请日期 2000.08.01
申请人 ORTHO-MCNEIL PHARMACEUTICAL, INC. 发明人 ABDEL-MAGID, AHMED, F.;HARRIS, BRUCE, D.;MARYANOFF, CYNTHIA, A.
分类号 C07C51/083;C07C59/86;C07C59/88;C07D231/12 主分类号 C07C51/083
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