EXPANSION OF A NOVEL CAG TRINUCLEOTIDE REPEAT IN THE 5' REGION OF THE PROTEIN PHOSPHATASE 2A PPP2R2B beta GENE IS ASSOCIATED WITH SCA12

摘要

Probes and primers useful for detecting changes in a particular microsatellite marker are provided. Expansions of the microsatellite are associated with a neurological disease with late onset. Thus determining expansions from a "normal" number can be used to track the inheritance of the disease within affected families.