发明名称 |
METHODS FOR INHIBITING BONE LOSS WITH 3,4-DIARYLCHROMAN |
摘要 |
Methods and pharmaceutical compositions for reducing bone loss are disclosed. 3,4-diarylchromans and their pharmaceutically acceptable salts are formulated into medicaments for the treatment of bone loss due to osteoporosis or other conditions. An exemplary 3,4diarylchroman is centchroman (3,4-trans-2,2-dimethyl-3phenyl-4-(p-(beta-pyrrolid inoethoxy) phenyl!-7-methoxy-chroman). Formulations include tablets and other forms suitable for administration and controlled-release subdermal implants.
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申请公布号 |
CA2157879(C) |
申请公布日期 |
2000.08.29 |
申请号 |
CA19942157879 |
申请日期 |
1994.01.13 |
申请人 |
ZYMOGENETICS, INC. |
发明人 |
LABROO, VIRENDER M.;PIGGOTT, JAMES R.;BAIN, STEVEN D. |
分类号 |
C07D311/58;A61K31/35;A61K31/352;A61K31/40;A61K31/4025;A61K31/55;A61P19/10;(IPC1-7):A61K31/35 |
主分类号 |
C07D311/58 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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