| 摘要 |
<p>A biologically-active microdispersion of a solid, water-insoluble biologically-active ingredient prepared by a process which comprises: a) liquifying the solid biologically-active ingredient, to produce a liquified biologically-active ingredient; b) mixing the liquified biologically-active ingredient with one or more surfactants and, optionally, one or more cosurfactants, to produce an a.i./surfactant mixture; c) adding water to the a.i./surfactant mixture, to produce a colloidal mixture; and d) equilibrating the colloidal mixture at a temperature at which the biologically-active ingredient is solidified, to produce the biologically-active microdispersion of the solid, water-insoluble biologically-active ingredient.</p> |
