发明名称 Certain fused pyrrolecarboxanilides; a new class of gaba brain receptor ligands
摘要 The present invention encompasses structures of the formula: or the pharmaceutically acceptable non-toxic salts thereof wherein: wherein: W represents substituted or unsubstituted phenyl; X is hydrogen, T is hydrogen, and n is 3, which compounds are highly selective agonists, antagonists or inverse agonists for GABAa brain receptors or prodrugs of agonists, antagonists or inverse agonists for GABAa brain receptors. These compounds are useful in the diagnosis and treatment of anxiety, sleep and seizure disorders, overdose with benzodiazepine drugs and for enhancement of memory.
申请公布号 US5925770(A) 申请公布日期 1999.07.20
申请号 US19980073030 申请日期 1998.05.05
申请人 NEUROGEN CORPORATION 发明人 ALBAUGH, PAMELA;HUTCHISON, ALAN
分类号 A61K31/404;C07C233/58;C07D209/08;C07D209/42;C07D209/52;C07D307/84;C07D401/12;C07D403/12;C07D405/12;C07D409/12;C07D413/04;C07D417/12;C07D471/04;(IPC1-7):C07D209/52 主分类号 A61K31/404
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