发明名称 METHOD OF PRODUCING VITAMIN PREPARATION: ASCORBIC ACID FOR INJECTIONS
摘要 FIELD: vitamin production. SUBSTANCE: aqueous solution containing 0.05 g ascorbic acid, 0.02385 g sodium bicarbonate, and 0.001 g sodium sulfate is subjected to sterilizing filtration and then powered out into ampoules. Sterilizing filtration is performed through membrane or cartridge filter with pore size 0.20-0.22 mcm. Preparation poured into ampoules is frozen at temperature from 45 to 55 C and dried in lyophilic mode at residual pressure no higher than 100 mcm Hg. EFFECT: increased preparation stability. 1 tbl
申请公布号 RU2125876(C1) 申请公布日期 1999.02.10
申请号 RU19970112648 申请日期 1997.07.25
申请人 UKADER MIKHAIL SEMENOVICH;SOFRONOV GENRIKH ALEKSANDROVICH;PENYSHKIN VLADIMIR IVANOVICH;FRIZER IVAN DITRIKHOVICH;GORJAJNOV VALERIJ NIKOLAEVICH;KOVALENKO ANATOLIJ ALEKSANDROVICH 发明人 UKADER M.S.;SOFRONOV G.A.;PENYSHKIN V.I.;FRIZEN I.D.;GORJAJNOV V.N.;KOVALENKO A.A.
分类号 A61K31/375;A61K9/08;A61P3/02;(IPC1-7):A61K31/375 主分类号 A61K31/375
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