发明名称 |
Hydrolyzed cellulose granulations for pharmaceuticals |
摘要 |
The present invention provides a method for preparing a spray-dried compressible granular formulation for preparing pharmaceutical tablets in which hydrolyzed cellulose is used as a granulation aid, the resulting granulations, and pharmaceutical tablets compressed from such granules. In these formulations there is employed from 1 to 97% by weight pharmaceutical active, from about 3 to 99% by weight hydrolyzed cellulose, based on the dry weight of the granulation, and optionally conventional granulation and/or tableting additives such as surfactants, disintegrants and antiadherents/flow aids.
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申请公布号 |
US5858409(A) |
申请公布日期 |
1999.01.12 |
申请号 |
US19960785228 |
申请日期 |
1996.04.17 |
申请人 |
FMC CORPORATION |
发明人 |
KARETNY, MARC S.;ERKOBONI, DAVID F.;VLADYKA, JR., RONALD S.;STAMATO, HOWARD J. |
分类号 |
A61K9/20;(IPC1-7):A61K9/14 |
主分类号 |
A61K9/20 |
代理机构 |
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地址 |
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