N- N-(3,3-DIMETHYLBUTYL)-L--g(a)-ASPARTYL]-L-HEXAHYDROPHENYLALANINE 1-METHYL ESTER USEFUL AS A SWEETENING AGENT AND METHOD OF PREPARATION

摘要

PCT No. PCT/FR95/00588 Sec. 371 Date Nov. 7, 1996 Sec. 102(e) Date Nov. 7, 1996 PCT Filed May 5, 1995 PCT Pub. No. WO95/30688 PCT Pub. Date Nov. 16, 1995Novel sweetening compound characterized in that it is N-[N-(3,3-dimethylbutyl)-L- alpha -aspartyl]-L-hexahydrophenylalanine 1-methyl ester of formula: and its method of preparation characterized in that an aqueous/alcohol solution of pH 4.5-5 of aspartame and 3,3-dimethylbutyraldehyde at room temperature is treated with hydrogen at a pressure of 3 bars in the presence of a catalyst based on platinum such as platinum black and platinum oxide and in that the product formed is purified by precipitation and filtration after evaporation in vacuo of the alcohol part of the solvent.