发明名称 |
SUBSTITUTED ALKYLDIAMINE DERIVATIVES AND THEIR USE AS TACHYKININ ANTAGONISTS. |
摘要 |
The present invention relates to novel substituted alkyldiamine derivatives of formula (1), wherein G1 and G2 are -CH2- or -C(O)-; Ar1 and Ar2 represent a radical chosen from the group (II), Ar3 is a radical chosen from the group (III). The compounds are useful tachykinin antagonists. Such antagonists are useful in the treatment of tachykinin-mediated diseases and conditions including asthma, cough, and bronchitis.
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申请公布号 |
MX9606654(A) |
申请公布日期 |
1997.12.31 |
申请号 |
MX19960006654 |
申请日期 |
1995.05.19 |
申请人 |
MERREL PHARMACEUTICALS INC. |
发明人 |
TIMOTHY P. BURKHOLDER;ELIZABETH KUDLACZ;TIEUBINH LE |
分类号 |
C07D309/12;A61K31/215;A61K31/35;A61K31/351;A61K31/403;A61K31/404;A61K31/405;A61P11/00;A61P43/00;C07C211/27;C07C211/29;C07C211/30;C07C223/02;C07C227/18;C07C229/36;C07C233/78;C07C237/20;C07C237/52;C07C271/20;C07C271/22;C07D209/14;C07D209/20;(IPC1-7):C07D209/20;A61K31/40 |
主分类号 |
C07D309/12 |
代理机构 |
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代理人 |
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主权项 |
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