发明名称 METHODS FOR IDENTIFYING INHIBITORS OF RNA VIRUSES
摘要 Assay methods are disclosed having utility in the identification of therapeutic agents effective against human hepatitis C virus and related viruses. NS3 protein derived from these viruses, representing a native and authentic version of the complete protein sequence, is used in the assay methods of the invention, which enables identification and development of anti-viral agents exhibiting inhibition of the protein's NTPase and RNA helicase activities.
申请公布号 WO9727334(A1) 申请公布日期 1997.07.31
申请号 WO1997US01614 申请日期 1997.01.17
申请人 VIROPHARMA INCORPORATED 发明人 COLLETT, MARC, S.;PEVEAR, DANIEL, C.;GROARKE, JAMES, M.;YOUNG, DOROTHY, C.
分类号 C12N15/09;A61K38/00;C07K14/18;C12N9/14;C12N9/50;C12N15/00;C12N15/40;C12Q1/68;C12Q1/70;C12R1/91;G01N33/15;(IPC1-7):C12Q1/70;C12N15/51;C12N9/99 主分类号 C12N15/09
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