发明名称 |
METHODS FOR IDENTIFYING INHIBITORS OF RNA VIRUSES |
摘要 |
Assay methods are disclosed having utility in the identification of therapeutic agents effective against human hepatitis C virus and related viruses. NS3 protein derived from these viruses, representing a native and authentic version of the complete protein sequence, is used in the assay methods of the invention, which enables identification and development of anti-viral agents exhibiting inhibition of the protein's NTPase and RNA helicase activities.
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申请公布号 |
WO9727334(A1) |
申请公布日期 |
1997.07.31 |
申请号 |
WO1997US01614 |
申请日期 |
1997.01.17 |
申请人 |
VIROPHARMA INCORPORATED |
发明人 |
COLLETT, MARC, S.;PEVEAR, DANIEL, C.;GROARKE, JAMES, M.;YOUNG, DOROTHY, C. |
分类号 |
C12N15/09;A61K38/00;C07K14/18;C12N9/14;C12N9/50;C12N15/00;C12N15/40;C12Q1/68;C12Q1/70;C12R1/91;G01N33/15;(IPC1-7):C12Q1/70;C12N15/51;C12N9/99 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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