发明名称 |
SArMV and sCYMVI hairpin ribozymes |
摘要 |
A method for the identification by modeling of synthetic catalytic RNAs and ribozymes thereof are disclosed including a hairpin portion and binding sites for cleaving an RNA substrate at a site which has a GUA sequence following the site of cleavage. Synthetic catalytic RNA has been modeled from negative strands of satellite RNA from the group consisting of chicory yellow mottle virus (sCYMVI) and arabis mosaic virus (sArMV).
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申请公布号 |
US5646031(A) |
申请公布日期 |
1997.07.08 |
申请号 |
US19950442513 |
申请日期 |
1995.05.16 |
申请人 |
NORTHERN ILLINOIS UNIVERSITY |
发明人 |
DEYOUNG, MARY BETH;SIWKOWSKI, ANDREW M.;HAMPEL, ARNOLD E. |
分类号 |
A61K38/00;C12N15/113;(IPC1-7):C07H21/04;C12Q1/68;A61K48/00;C12N15/85 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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