Triazine derivative, chymase activity inhibitor and nitric oxide production inhibitor

摘要

The present invention provides novel triazine derivatives which inhibit chymase activity and nitric oxide production. The triazine derivatives are useful for the prevention and treatment of bronchial asthma, allergic rhinitis and hives by inhibiting chymase activity, and are useful for the prevention and treatment of cardiopathy and cerebrovascular disease, ishemic heart disease, septic shock, ache, rheumatic fever, arthritis, asthma, immunodeficiency, viral or non-viral infections, autoimmune diseases and cancer by inhibiting nitric oxide production.