| 摘要 |
<p>A benzofuran derivative represented by general formula (1) and a medicine containing the same, wherein R1 represents hydrogen, hydroxy or C¿1?-C5 alkoxy; R?2 and R3¿ represent each hydrogen, C¿1?-C5 alkyl or C2-C5 alkynyl; and R?4¿ represents C¿1?-C8 alkyl, C2-C8 alkoxy, or benzoyloxy which may be substituted by one or two hydroxy groups, provided R?4¿ is not n-pentyl when R1 is hydroxy and R?2 and R3¿ are both hydrogen. This compound has a remarkable effect of inhibiting 5-lipoxygenase and also excellent antiallergic and anti-inflammatory effects, and is useful as a remedy or preventive for allergic diseases such as bronchial asthma, rheumatic diseases, and inflammations including psoriasis.</p> |
