发明名称 THERAPEUTIC USES OF KERATINOCYTE GROWTH FACTOR
摘要 Based on extensive in vivo studies in animals, it has now been discovered that KGF stimulates proliferation, growth and differentiation in various cells of epithelial tissue, besides keratinocytes. This better understanding of the biological effects of KGF in vivo enables the use of this polypeptide as a therapeutic agent, suitably 'formulated in a pharmaceutical composition, for the specific treatment of disease states and medical conditions afflicting tissues and organs such as the dermal adnexae, the liver, the lung, and the gastrointestinal tract.
申请公布号 CA2159109(A1) 申请公布日期 1994.10.13
申请号 CA19942159109 申请日期 1994.03.24
申请人 AMGEN INC. 发明人 PIERCE, GLENN F.;HOUSLEY, REGINA M.;MORRIS, CHARLES F.
分类号 C12N15/09;A61K;A61K8/00;A61K8/99;A61K38/00;A61K38/16;A61K38/22;A61P1/04;A61P1/16;A61P11/00;A61P17/02;A61P17/14;A61Q5/00;C07K;C07K14/50;C12N5/06;C12N15/12;C12P21/02;(IPC1-7):C12N5/02;A61K38/18 主分类号 C12N15/09
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