| 摘要 |
A method for controlling the formation of a microemulsion of fluorinated oils and water is disclosed. In particular, the addition of mixtures of fluorinated and hydrogenated surfactant to fluorinated oil and water is used to create a fluorinated oil microemulsion. The degree of hydrophilicity of the selected hydrogenated surfactant controls the temperature at which the microemulsion forms. The amphiphilic strength of the selected hydrogenated surfactant controls the concentration of fluorinated surfactant required for microemulsification of the fluorinated oil and water. As shown in figure 4, in forming a microemulsification containing water, perfluorodecalin, zonyl FSO-100(n-alkyl polyglycol ether with a perfluorinated alkyl chain) and C12E1 (hydrogenated surfactant produced by reacting C12, alkanol with 1 mol of ethylene oxide), the addition of increased concentrations of C12E1, lowers the temperature at which the microemulsion forms. The microemulsions are useful in treating body organs and delivering medicaments. |
