Procédé d'obtention de protéines membranaires, et utilisation de ces protéines dans un but de diagnostic ou de vaccination.

摘要

A method for the lysis of micro-organisms such as viruses, in particular for preparing and, if required, purifying membrane proteins in said micro-organisms, wherein any proteins which may be present in oligomeric form are preserved in that form while the infectiousness of the micro-organisms is destroyed. Said method is characterized in that it includes the step of treating said micro-organisms with a composition containing a combination of at least two different amphipathic molecules. The use of the resulting oligomeric proteins in diagnostic methods or vaccine compositions is also disclosed.