摘要 |
PCT No. PCT/US92/03317 Sec. 371 Date May 23, 1994 Sec. 102(e) Date May 23, 1994 PCT Filed Apr. 28, 1992 PCT Pub. No. WO92/21677 PCT Pub. Date Dec. 10, 1992Compounds of the formula <IMAGE> I wherein R1 is methoxy and R2 is selected from the group consisting of methyl, ethyl, isopropyl, sec-butyl and tert-butyl; and the pharmaceutically acceptable salts of such compounds. These compounds are substance P antagonists and useful in the treatment of gastrointestinal disorders, inflammatory disorders, central nervous system disorders and pain. |