发明名称 |
A CONTROLLED, SUSTAINED RELEASE DELIVERY SYSTEM FOR TREATING DRUG DEPENDENCY |
摘要 |
A drug delivery system useful in treating an individual for a drug dependence is described. One embodiment of the system is useful for aiding individuals in the cessation of smoking or chewing nicotine containing products is described. The delivery system includes a physical constraint modulation system (PCMS<TM>) containing lobeline. The drug delivery system is capable of delivering lobeline to an individual in a controlled, sustained release manner and providing long-term therapeutic levels of lobeline to the individual. The delivery of lobeline in such a manner reduces or eliminates the individual's smoking or chewing habit. The PCMS may be a biodegradable polymer containing the lobeline capable of subcutaneous or intramuscular injection or implantation into the individual or may be part of a transdermal patch containing lobeline. Also described are methods of using the drug delivery systems in treating other drug dependencies and kits containing the drug delivery systems. |
申请公布号 |
WO9219226(A1) |
申请公布日期 |
1992.11.12 |
申请号 |
WO1992US03859 |
申请日期 |
1992.05.07 |
申请人 |
DYNAGEN, INC. |
发明人 |
KITCHELL, JUDITH, P.;MUNI, INDU, A.;BOYER, YVONNE, N. |
分类号 |
A61K9/00;A61K9/08;A61K9/16;A61K9/70;A61K31/445 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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